News

New service: mim-tRNA sequencing 


Based on customer requests, omiics now offer optimized mim-tRNA sequencing as a service


Transfer RNAs (tRNAs) are short, abundant transcripts needed for translating messenger RNA into protein. As such, the composition of cellular tRNA pools impact proteome dynamics and integrity. tRNA expression is dynamically regulated in different tissues and during development, and defective tRNA biogenesis is linked to neurological disorders and cancer.

Classic next generation sequencing has been challenged in measuring cellular tRNA abundance, due to pervasive blocks of cDNA synthesis at modified nucleosides and the extensive similarity among tRNA genes. Mim-tRNA sequencing overcome these issues and uncover a dramatic heterogenety of tRNA isodecoder pools between human cell lines and also showed there to be a interdependence of modifications within an individual tRNA transcript


see the reference paper


2022.02.07 | SUSANNE TRILLINGSGAARD VENØ

RNA Mechanisms & Therapeutics in Metabolic Disease 2021


Meet omiics CTO Morten Venø at the conference in Copenhagen 1.-3. dec 2021


At the conference in Copenhagen, omiics founder and CTO Morten Venø  presented a customer project on RNA biomarkers in cell-free bioliquids; specifically detection of miRNA, circRNA and tRNA fragments in bile. 


read the program here


2021.12.01 | SUSANNE TRILLINGSGAARD VENØ

New national network: NGS Tech


Interview with omiics CEO Susanne Trillingsgaard Venø about her role in a new national experience network


Read about the the ideas and efforts behind establishing a new national network across NGS entusiasts from academia, hospitals and industry in Denmark


read full text here


2021.11.16 | SUSANNE TRILLINGSGAARD VENØ


Novel method for sequencing full-length circRNAs to characterize exon usage, intron retention and microexons


omiics publication in Nature communication


In 2021, a method paper was published in Nature Communication on the usage of long-read sequencing technology. The method circumvents previous analyse limitation of circRNA, as the use of short-read Illumina sequencing only allowed detection of circRNAs, but did not support full-length characterization. In this work, omiics developed the bioinformatic pipeline for both the initial analysis and the circRNA panel.


read more here


2021.08.30 | SUSANNE TRILLINGSGAARD VENØ

New Website for PRIME


The ERC FET OPEN Consortium - PRIME has a new webpage


In 2020, omiics partnered on a successful ERC FET Open Grant, PRIME. The project has a new website! You can now read more about how omiics will provide expertise in low input RNA sequencing and bioinformatics analysis for this innovative and exciting project! 


read more here


2021.06.29 | SUSANNE TRILLINGSGAARD VENØ

OMIICS featured in Medical Writting


omiics CEO Susanne Trillingsgaard Venø featured in article on mentorship in start-ups


Read about the journey of our company and our leadership on this feature piece authored by Susanne herself. 


read full text here



2021.06.21 | SUSANNE TRILLINGSGAARD VENØ

Developing biological nano-implants to block epileptic seizures


omiics publication featured in Aarhus University news


Epilepsy is one of the most common neurological diseases, and seizures can be debilitating. Unfortunately, treatments to prevent these seizures are lacking. Jørgen Kjems from iNANO and the Department of Molecular Biology at Aarhus University and the AU spinout company, OMIICS, are partners in a new consortium, PRIME, that will seek to develop biological nano-implants - based on naturally occurring signaling pathways - that can help patients with epilepsy.


read full text here


2021.03.10 | ANNE FÆRCH NIELSEN



Large-scale data sets identify small RNAs with a role in epilepsy


omiics publication featured in Aarhus University news


A new paper from Jørgen Kjems' group at iNANO and MBG describes how expression of non-coding RNA changes during epileptic seizures in rodents. The authors found that inhibiting a specific set of microRNAs (miRNAs) by antisense technology reduced seizure frequency in a mouse model, suggesting that these RNA molecules could serve as possible targets for future epilepsy therapy.


read full text here


2020.06.25 | ANNE FÆRCH NIELSEN

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