The high dynamic range in NGS allows the detection very small differences in expression patterns between samples. This also allows for sequencing of low-input samples.
TYPES OF SAMPLES:
Tissues, cells, powders, biofluids (CSF, bile, saliva, exosomes, IVF media), and others.
Map all differences
(e.g. effect of treatment/mutation)
Spot the trend
(e.g. identify biomarkers)
At omiics, you will have expert sample sample preparation, sequencing, data processing, coding, and interpretation of the results. Having NGS experts by your side through the whole process ensures you can trust your results and focus on the science.
The result of NGS are patterns of RNA expression. By quantifying changes in RNA levels, we can pin-point the expression of every gene that is being turned up or down. Through advanced bioinformatics this enables mapping of cellular pathways likely affected.